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논문검색

학회지 > 논문검색
논문 검색
Yoon Ho Sohn, Nak Kwan Sung, Mu Sang Lee Young Ho Lee, Won Sik Kim*
"Department of Plastic and Reconstructive Surgery Daegu Fatima Hospital., Department of Anatomy, College of Medicine, Chungnam National University.*"
"AN ULTRASTRUCTURAL STUDY OF THE CHANGES OF ELASTIC FIBER IN AGED SKIN"
J Korean Soc Aesth Surg 1995 (Mar) 001(08) 77-91
Aging, Elastic fiber
Ksaps001-01-08.pdf Ksaps001-01-08.pdf
This study was carriedd out to investigate the changes of elastic fibers in aged skin, from age 10 to 79 years old.
  Biopsied normal skin was studied with light microscope and transmission electron microscope, usging both conventional and tannic acid stain.
  Normal mature skin revealed three types of elastic fibers, oxytalan. elaunin and mature elastic fibers. The oxytalan fibers were mostly composed of microfibrillar protein, The elastin protein was progressively accumulated in the microfibrillar mantle and forming mature elastic figers. 
 From age 30, abnormalities of elastic fibers were exhibited, loss of oxytalan fibers was the initial sign of aging process of elastic fibers. The mature elastic fibers showed pores and splitting of elastin matrix with fragmentation. Fine granular materials were scattered near the elastin. Phagocytosis of degenerated elastin by tissue macrophages was noted.
  From the above results, it is concluded that aging processes of elastic fibers begin at age 30 with a disappearance of oxytalan fiber that may be linked with the functional changes of fibroblasts, both production and degradation activity
"손윤호 · 성낙관 · 이무상, 이영호 · 김원식* "
대구 파티마병원 성형외과학교실, 충남대학교 의과대학 해부학교실*
나이에따른피부탄력섬유의미세형태학적연구
1995 (Mar) 001(08) 77-91