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논문검색

학회지 > 논문검색
논문 검색
Ja Hea Gu, M.D., Seung-Kyu Han, M.D., Ph.D.
Department of Plastic Surgery, Korea University College of Medicine, Seoul, Korea
Brief Review of Adipose Derived Cells
J Korean Soc Aesthetic Plast Surg 2009 (Oct) 015(02) 192-198
Mesenchymal stem cell, Adipose stem cell, Cell therapy
Ksaps015-03-02.pdf Ksaps015-03-02.pdf
Recent works state that adipose tissue hosts cells which are able to display various differentiation
potentials. Moreover, this adult tissue is abundant and easy to sample with no ethic limitation. In
addition, the simple isolation procedures provide a clear advantage for tissue engineering. The
adipose cells which are used for tissue engineering can be isolated from the stromal vascular fraction
(SVF) obtained after adipose tissue digestion that may be used either freshly prepared or after
culture. In this last case, cultured cells represent a particular cell subpopulation, which is restricted
to the adherent cell fraction of SVF, and termed adipose derived stromal cells (ADSCs). However,
there is a confusing inconsistency in the literature in the use of terms to describe multipotent
precursor cells from adipose tissue stroma, such as processed lipoasporate cells, ADSCs, preadipocytes,
adipose stoma vascular cell fraction, SVF cells, and others. In addition, characteristics of
such cells have not clearly been defined and still controversial. The aim of this brief and comprehensive
review is to define terminologies for such cells, to describe preparation and isolation
procedures for SVF cells and ADSCs, to summarize molecular characterization of SVF cells and
ADSCs, and to discuss clinical cases using these cells.
구자혜 ‧ 한승규
고려대학교 의과대학 성형외과학교실
임상의를 위한 지방유래세포의 이해
2009 (Oct) 015(02) 192-198