Autologous fat graft became generalized with structural microfat graft by Coleman. Functioning as an important surgical technique for plastic surgeons, it has been utilized not only in augmentation of facial soft tissue, but also as biological fillers and anti-aging procedures. For maximal survival and minimal resorption of the grafted fat tissue, meticulous caution must be taken in all process of the autologous fat graft from selection of the donor site to aspiration, refinement, injection and replacement. This article emphasizes the techniques, such as selection of adequate anesthesia, selection of cannula for injection, injection technique, replacement layer and volume for in the fat tissue to be injected for operating plastic surgeons who are at initial stage of autologous fat graft. Autologous fat graft techniques by Coleman, multi layer injection technique, minimal volume injection technique, meticulous handling of fat tissue and minimal hemorrhage are generalized concepts and knowledge with must be acquired by the operator. However, the amount of injection and degree of over-correction must be carefully considered.